ZHICHENG BIO
Amino AcidsIn stock
L-Arginine Base
USP32
$3.25 – $3.64 /kgby order volume
01Product
L-Arginine HCl 83% Arginine
At a glance
L-Arginine HCl from Zhicheng Bio — supply summary
Zhicheng Bio supplies bulk L-Arginine HCl (83% Arginine), CAS 1119-34-2, shipping from Shanghai, China. This grade is produced to order. Every shipment carries a batch Certificate of Analysis; specification sheet and MSDS are supplied on request. Zhicheng Bio publishes no list price — quotes are issued per quantity and Incoterm by email to zhicheng1@zhicheng-bio.cn.
- Supplier
- Zhicheng Bio, Shanghai, China
- CAS number
- 1119-34-2
- Molecular formula
- C6H14N4O2·HCl
- Grade / specification
- 83% Arginine
- Availability
- Made to order
- Documents
- Batch CoA with every shipment; spec sheet and MSDS on request
- Packing
- 25 kg cartons or bags, adjustable
- PubChem CID
- 66250
- How to get a price
- Email RFQ to zhicheng1@zhicheng-bio.cn — no list price is published
Amino Acids
In stock
L-Arginine HCl
83% Arginine
CAS 1119-34-2 · C6H14N4O2·HCl
Bulk L-Arginine HCl for B2B manufacturing — supplied against your target specification, with documentation your QA can review before anything ships. Pricing below is indicative; send an RFQ for a firm quote, MOQ and lead time.
$3.69 – $4.14 /kg
by order volume · indicative, ex-Shanghai
Indicative range — larger volumes price toward the low end. Ingredient markets move weekly; your firm price is confirmed by quotation, typically within one business day.
Key supply points
- Supplied against your target specification — USP / FCC / JP monograph where applicable
- Recent batch COA provided with the quotation, before you commit
- Consolidates with other SKUs into one shipment out of Shanghai
- Third-party lab verification available pre-shipment on request
Documentation with every batch
COA per batchSpec SheetMSDS / SDSExport docs
Third-party lab verification can be arranged pre-shipment on request. Certificates of origin, non-GMO or allergen statements per destination-market requirements.
Shipping & Lead Time
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Documentation-first
COA per batch, Spec Sheet and MSDS — reviewed by your QA before anything ships.
Ready-stock depth
Multi-tonne inventory on core SKUs, plus 28 actives held in our US warehouse in Los Angeles for domestic delivery.
Certified supply chain
Sourced from audited, certified manufacturers — ISO, HACCP, Halal & Kosher available.
Flexible export
25 kg bags, cartons or drums; FOB / CIF / DDP by lane, sea or air consolidation.
02Identity & properties
Identity & properties
Compound identifiers and physical properties for this material. The binding version is always the Specification Sheet and batch COA issued with your quotation.
| CAS No. | 1119-34-2 |
|---|---|
| Molecular Formula | C6H15ClN4O2 (written as C6H14N4O2·HCl) |
| Molecular Weight | 210.66 |
| EINECS | 214-275-1 (PubChem also lists 239-674-8) |
| Synonyms | L-Arginine monohydrochloride, L-Arginine HCl, Arginine hydrochloride |
| Appearance | White crystalline powder |
| Solubility | Freely soluble in water; practically insoluble in ethanol and ether |
| Pharmacopoeial reference | FCC · JP (as L-Arginine Hydrochloride) |
03Specifications
Specifications
Typical parameters below — the binding version is the Specification Sheet and batch COA we send with your quotation.
| Parameter | Specification | Test method |
|---|---|---|
| Arginine content (free base equivalent) | 82.7% theoretical (offer sheet states 83%) | Calculated from molecular weights |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
A dash means we have no fixed limit to publish for that parameter: it is reported on the batch COA and the limit is agreed with your QA. We would rather leave it blank than invent a number. Full physical, chemical, heavy-metal and microbiological parameters are listed in the Specification Sheet — sent with every quotation.
04Formulation & handling notes
Formulation & handling notes
The practical points our technical team raises with buyers of this material — the things that decide whether a batch behaves in your process.
01
The whole reason to buy the hydrochloride instead of the base is pH. Arginine free base gives a strongly alkaline solution (its guanidino group has a pK around 13); the hydrochloride is the near-neutral form that will not fight an existing beverage buffer. If your formula is a flavoured drink, the HCl salt is almost always the right choice.
02
The second reason is CO2. The free base absorbs carbon dioxide from air, which slowly forms carbonate and drifts pH and titratable assay; the hydrochloride does not behave that way, which makes it far more forgiving in a plant with open handling.
03
The cost of both benefits is potency: 82.7% arginine (174.20/210.66) against 100% for the base. A 3000 mg arginine claim needs 3628 mg of the hydrochloride. This is the single most common label error when a formula is switched between arginine forms.
04
The chloride is not free of consequences. It shows up in the chloride limit test of an amino-acid monograph, in your product's total sodium-chloride-equivalent calculation if you report one, and in corrosion of stainless equipment held wet with concentrated solution.
05
For parenteral and clinical use, arginine hydrochloride rather than the base is the form with a JP Injection monograph — a useful signal of which form the pharmaceutical world has standardised on.
05Applications
Applications
B2B manufacturing use only — no finished-product or health claims.
Pre-workout and pump formulations where solution pH must stay near neutral
Ready-to-drink and effervescent formats
Free-form amino acid and EAA blends
Clinical and parenteral nutrition raw material
Cosmetic and personal-care formulations
Buffer and cell-culture media preparation
06Regulatory status by market
Regulatory status by market
Status of the raw material, stated as conservatively as our sources allow. This is supply-chain information, not regulatory advice — confirm the position for your finished product and destination market with your own regulatory counsel.
| Market | Status | Basis |
|---|---|---|
| United States | Listed by name in FDA's food-additive regulation for amino acids as 'L-Arginine'. That regulation permits use as a nutrient 'to significantly improve the biological quality of the total protein' of a food, subject to a cap of 6.6 percent by weight of the total protein of the finished food, and to the labelling requirements in paragraph (e). It is not a general-purpose clearance for any food use, and it is not the authority under which dietary supplements are marketed — those sit under DSHEA and 21 CFR part 111. | 21 CFR 172.320(a), (b), (c)(4), (e) |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| Japan | An Official Monograph titled 'L-Arginine Hydrochloride' is listed in the Japanese Pharmacopoeia, Eighteenth Edition. Monograph existence only — no limits transcribed. | JP XVIII, Official Monographs |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
07Selected research
Selected research
Peer-reviewed literature on this compound, with linked identifiers so you can read the primary source rather than take our word for it.
These references are listed for scientific context only. They describe published research on the compound; they are not claims about this raw material and not claims about any finished product. Zhicheng Bio makes no medical, health or performance claims.
- In a randomised placebo-controlled study in seventeen healthy men, a single 6 g oral dose of L-arginine hydrochloride produced no significant change in plasma nitrite plus nitrate over 120 minutes. Alvares TS, Conte-Junior CA, Silva JT, Paschoalin VM. Nutr Metab (Lond). 2012;9(1):54. PMID 22691607DOI 10.1186/1743-7075-9-54Source
- In a crossover pharmacokinetic study in ten healthy volunteers, the absolute bioavailability of a single 10 g oral dose of L-arginine was approximately 20%. Tangphao O, Grossmann M, Chalon S, Hoffman BB, Blaschke TF. Br J Clin Pharmacol. 1999;47(3):261-266. PMID 10215749DOI 10.1046/j.1365-2125.1999.00883.xSource
- In rats and rabbits, oral supplementation with a combination of L-citrulline and L-arginine produced a more rapid increase in plasma L-arginine and greater enhancement of nitric oxide bioavailability than either compound alone at the same total dose. Morita M, Hayashi T, Ochiai M, Maeda M, Yamaguchi T, Ina K, Kuzuya M. Biochem Biophys Res Commun. 2014;454(1):53-57. PMID 25445598DOI 10.1016/j.bbrc.2014.10.029Source
08Packing, storage & lead time
Packing, storage & lead time
| Standard packing | 25 kg bags, cartons or drums |
|---|---|
| Private packing | Custom packing & labeling available for regular customers |
| Storage | Cool, dry place, sealed in original packaging |
| Lead time | In stock |
| Shipping | Sea or air consolidation out of Shanghai · FOB / CIF / DDP by lane |
09Procurement FAQ
Procurement FAQ
01Base or hydrochloride for a flavoured drink?
Hydrochloride, nearly always. The free base is strongly alkaline and will push your pH up and pick up CO2 from the air; the HCl salt is near-neutral and behaves itself in an open plant. You give up potency: 82.7% arginine versus 100%.
02How much HCl salt equals a 3000 mg arginine claim?
3628 mg, from the 82.7% free-base equivalent. Tell us on the RFQ whether your target is arginine or salt weight — this is where most arginine orders go wrong.
03Do you have a monograph grade?
There are FCC and JP monographs for L-arginine monohydrochloride, and JP additionally has an Injection monograph for it. Tell us which monograph and which edition you need to comply with and we will get the manufacturer to confirm against it in writing before shipment.
04Any issue with chloride in my process?
Two to watch. Chloride shows up in the monograph chloride limit test, and concentrated arginine HCl solution left standing on stainless steel is a corrosion risk. Neither is a problem at normal use levels, but both are worth a line in your process risk assessment.
05What is the MOQ for L-Arginine HCl?
MOQ is quote-based and flexible. Tell us your target quantity in the RFQ — for core in-stock SKUs we can usually accommodate both trial orders and multi-tonne volumes.
06Can I get a sample of L-Arginine HCl before ordering?
Yes — samples are available on request for evaluation and lab verification. Mention it in your RFQ and we will confirm the arrangement.
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