L-Carnitine HCl
L-Carnitine HCl from Zhicheng Bio — supply summary
Zhicheng Bio supplies bulk L-Carnitine HCl, CAS 6645-46-1, shipping from Shanghai, China. This grade is produced to order. Every shipment carries a batch Certificate of Analysis; specification sheet and MSDS are supplied on request. Sourced to order — about 1 week to Shanghai port. Zhicheng Bio publishes no list price — quotes are issued per quantity and Incoterm by email to zhicheng1@zhicheng-bio.cn.
- Supplier
- Zhicheng Bio, Shanghai, China
- CAS number
- 6645-46-1
- Molecular formula
- C7H15NO3·HCl
- Availability
- Made to order
- Documents
- Batch CoA with every shipment; spec sheet and MSDS on request
- Packing
- 25 kg cartons or bags, adjustable
- PubChem CID
- 656657
- How to get a price
- Email RFQ to zhicheng1@zhicheng-bio.cn — no list price is published
L-Carnitine HCl
Bulk L-Carnitine HCl for B2B manufacturing — supplied against your target specification, with documentation your QA can review before anything ships. Pricing below is indicative; send an RFQ for a firm quote, MOQ and lead time.
Indicative range — larger volumes price toward the low end. Ingredient markets move weekly; your firm price is confirmed by quotation, typically within one business day.
Key supply points
- Supplied against your target specification — USP / FCC / JP monograph where applicable
- Recent batch COA provided with the quotation, before you commit
- Consolidates with other SKUs into one shipment out of Shanghai
- Third-party lab verification available pre-shipment on request
Documentation with every batch
Third-party lab verification can be arranged pre-shipment on request. Certificates of origin, non-GMO or allergen statements per destination-market requirements.
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Documentation-first
COA per batch, Spec Sheet and MSDS — reviewed by your QA before anything ships.
Ready-stock depth
Multi-tonne inventory on core SKUs, plus 28 actives held in our US warehouse in Los Angeles for domestic delivery.
Certified supply chain
Sourced from audited, certified manufacturers — ISO, HACCP, Halal & Kosher available.
Flexible export
25 kg bags, cartons or drums; FOB / CIF / DDP by lane, sea or air consolidation.
Identity & properties
Compound identifiers and physical properties for this material. The binding version is always the Specification Sheet and batch COA issued with your quotation.
| CAS No. | 6645-46-1 |
|---|---|
| Molecular Formula | C7H16ClNO3 (written as C7H15NO3·HCl) |
| Molecular Weight | 197.66 |
| EINECS | 229-663-6 |
| Synonyms | Levocarnitine hydrochloride, L-Carnitine HCl, (R)-carnitine hydrochloride, vitamin BT hydrochloride |
| Appearance | White crystalline powder |
| Solubility | Freely soluble in water |
Specifications
Typical parameters below — the binding version is the Specification Sheet and batch COA we send with your quotation.
| Parameter | Specification | Test method |
|---|---|---|
| L-Carnitine content (free base equivalent) | 81.6% theoretical | Calculated from molecular weights |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
A dash means we have no fixed limit to publish for that parameter: it is reported on the batch COA and the limit is agreed with your QA. We would rather leave it blank than invent a number. Full physical, chemical, heavy-metal and microbiological parameters are listed in the Specification Sheet — sent with every quotation.
Formulation & handling notes
The practical points our technical team raises with buyers of this material — the things that decide whether a batch behaves in your process.
The reason salts of carnitine exist at all is moisture: carnitine free base is so hygroscopic that it is impractical as a dry powder, which is why the trade sells the hydrochloride and the L-tartrate. Between the two salts, the HCl is the higher-potency one at 81.6% carnitine (161.20/197.66) versus 68% for the tartrate.
The HCl salt makes an acidic solution, so it fits naturally into low-pH beverages and shots but will shift the pH of an unbuffered blend downward — the opposite direction from the tartrate at equal carnitine load.
Chloride load matters in two places: a chloride-sensitive analytical method (the chloride limit test in an amino-acid monograph) and stainless-steel process equipment held wet. Both are non-issues with the tartrate.
Because it is the highest-potency carnitine salt on this list, it is the one to use when the label needs a high carnitine number in a small capsule — 500 mg carnitine needs about 613 mg of the HCl versus about 735 mg of the tartrate.
Any switch between carnitine salt forms must be recalculated on the free-base equivalent, and the counter-ion (chloride versus tartrate) has to be declared correctly in the ingredient statement.
Applications
B2B manufacturing use only — no finished-product or health claims.
Regulatory status by market
Status of the raw material, stated as conservatively as our sources allow. This is supply-chain information, not regulatory advice — confirm the position for your finished product and destination market with your own regulatory counsel.
| Market | Status | Basis |
|---|---|---|
| United States | L-carnitine is not one of the amino acids listed in FDA's amino-acid food-additive regulation (21 CFR 172.320) — that list does not include carnitine in any form. Two GRAS notices for levocarnitine/L-carnitine-L-tartrate were withdrawn at the notifier's request (GRN 362 in 2011, GRN 935 in 2020); GRN 993 for L-carnitine-L-tartrate closed with 'FDA has no questions' in 2021 but for infant formula only. Dietary supplement use rests on DSHEA, not on any of these. | 21 CFR 172.320; FDA GRAS Notice Inventory GRN 362, 935, 993 |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
| Japan | No JP XVIII Official Monograph for this substance was located. | JP XVIII |
Selected research
Peer-reviewed literature on this compound, with linked identifiers so you can read the primary source rather than take our word for it.
These references are listed for scientific context only. They describe published research on the compound; they are not claims about this raw material and not claims about any finished product. Zhicheng Bio makes no medical, health or performance claims.
- A pharmacokinetic review reported that after oral doses of 1-6 g the absolute bioavailability of L-carnitine is 5-18%, whereas the bioavailability of dietary L-carnitine may be as high as 75%. Evans AM, Fornasini G. Clin Pharmacokinet. 2003;42(11):941-967. PMID 12908852DOI 10.2165/00003088-200342110-00002Source
- A review of carnitine kinetics reported bioavailability of dietary L-carnitine at 54-87%, absorption of 0.5-6 g supplemental doses as primarily passive with 14-18% bioavailability, and a whole-body turnover time of 38-119 hours at normal dietary intake. Rebouche CJ. Ann N Y Acad Sci. 2004;1033:30-41. PMID 15591001DOI 10.1196/annals.1320.003Source
- A systematic review of oral L-carnitine supplementation grouped trials by exercise intensity and examined which doses and timings had been used across the moderate- and high-intensity literature. Mielgo-Ayuso J, Pietrantonio L, Viribay A, Calleja-González J, González-Bernal J, Fernández-Lázaro D. Nutrients. 2021;13(12):4359. PMID 34959912DOI 10.3390/nu13124359Source
Packing, storage & lead time
| Standard packing | 25 kg bags, cartons or drums |
|---|---|
| Private packing | Custom packing & labeling available for regular customers |
| Storage | Cool, dry place, sealed in original packaging |
| Lead time | Sourced to order — about 1 week to Shanghai port |
| Shipping | Sea or air consolidation out of Shanghai · FOB / CIF / DDP by lane |

