L-Carnitine HCl
L-Carnitine HCl —— 致诚生物供货速览
致诚生物(Zhicheng Bio)从中国上海供应L-Carnitine HCl,CAS 6645-46-1,非现货,按单排产,每批次随货提供 COA,可另附规格书与 MSDS。按单备货——约1周到上海。询盘请发 zhicheng1@zhicheng-bio.cn,官网不挂价,报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio,上海
- CAS 号
- 6645-46-1
- 分子式
- C7H15NO3·HCl
- 现货状态
- 按单排产
- 随货文件
- 批次 COA;规格书、MSDS 可索取
- 包装
- 25 kg 纸箱/袋,可按需调整
- PubChem CID
- 656657
- 报价方式
- 邮件询盘(zhicheng1@zhicheng-bio.cn),官网不展示价格
L-Carnitine HCl
L-Carnitine HCl 大宗原料,仅面向 B2B 生产采购——按您的目标规格供货,发货前先提供文件供质检审核。以下为指导价;发送询盘获取正式报价、起订量与交期。
价格为到上海交货指导区间,采购量越大越接近低端;原料行情每周波动,具体以询盘报价为准,通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA,下单前先过您的QA
- 可与其他SKU拼单,上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
发货前可按需安排第三方检测;产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存,现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装;FOB/CIF/DDP按航线,海运空运均可拼货。
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 6645-46-1 |
|---|---|
| 分子式 | C7H16ClNO3 (written as C7H15NO3·HCl) |
| 分子量 | 197.66 |
| EINECS | 229-663-6 |
| 别名 | Levocarnitine hydrochloride, L-Carnitine HCl, (R)-carnitine hydrochloride, vitamin BT hydrochloride |
| 外观 | White crystalline powder |
| 溶解性 | Freely soluble in water |
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| L-Carnitine content (free base equivalent) | 81.6% theoretical | Calculated from molecular weights |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目,表示我们没有可对外公布的固定限度:该项目在批次COA中如实报出,限度与您的质检共同确认。宁可留空,也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
The reason salts of carnitine exist at all is moisture: carnitine free base is so hygroscopic that it is impractical as a dry powder, which is why the trade sells the hydrochloride and the L-tartrate. Between the two salts, the HCl is the higher-potency one at 81.6% carnitine (161.20/197.66) versus 68% for the tartrate.
The HCl salt makes an acidic solution, so it fits naturally into low-pH beverages and shots but will shift the pH of an unbuffered blend downward — the opposite direction from the tartrate at equal carnitine load.
Chloride load matters in two places: a chloride-sensitive analytical method (the chloride limit test in an amino-acid monograph) and stainless-steel process equipment held wet. Both are non-issues with the tartrate.
Because it is the highest-potency carnitine salt on this list, it is the one to use when the label needs a high carnitine number in a small capsule — 500 mg carnitine needs about 613 mg of the HCl versus about 735 mg of the tartrate.
Any switch between carnitine salt forms must be recalculated on the free-base equivalent, and the counter-ion (chloride versus tartrate) has to be declared correctly in the ingredient statement.
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息,不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | L-carnitine is not one of the amino acids listed in FDA's amino-acid food-additive regulation (21 CFR 172.320) — that list does not include carnitine in any form. Two GRAS notices for levocarnitine/L-carnitine-L-tartrate were withdrawn at the notifier's request (GRN 362 in 2011, GRN 935 in 2020); GRN 993 for L-carnitine-L-tartrate closed with 'FDA has no questions' in 2021 but for infant formula only. Dietary supplement use rests on DSHEA, not on any of these. | 21 CFR 172.320; FDA GRAS Notice Inventory GRN 362, 935, 993 |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
| Japan | No JP XVIII Official Monograph for this substance was located. | JP XVIII |
相关研究文献
本化合物的同行评议文献,标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究,既不是对本原料的宣称,也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- A pharmacokinetic review reported that after oral doses of 1-6 g the absolute bioavailability of L-carnitine is 5-18%, whereas the bioavailability of dietary L-carnitine may be as high as 75%. Evans AM, Fornasini G. Clin Pharmacokinet. 2003;42(11):941-967. PMID 12908852DOI 10.2165/00003088-200342110-00002原文
- A review of carnitine kinetics reported bioavailability of dietary L-carnitine at 54-87%, absorption of 0.5-6 g supplemental doses as primarily passive with 14-18% bioavailability, and a whole-body turnover time of 38-119 hours at normal dietary intake. Rebouche CJ. Ann N Y Acad Sci. 2004;1033:30-41. PMID 15591001DOI 10.1196/annals.1320.003原文
- A systematic review of oral L-carnitine supplementation grouped trials by exercise intensity and examined which doses and timings had been used across the moderate- and high-intensity literature. Mielgo-Ayuso J, Pietrantonio L, Viribay A, Calleja-González J, González-Bernal J, Fernández-Lázaro D. Nutrients. 2021;13(12):4359. PMID 34959912DOI 10.3390/nu13124359原文
包装、储存与交期
| 标准包装 | 25kg袋装、箱装或桶装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处,原包装密封保存 |
| 交期 | 按单备货——约1周到上海 |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |

