L-Glutamine FCC
L-Glutamine —— 致诚生物供货速览
致诚生物(Zhicheng Bio)从中国上海供应L-Glutamine(FCC),CAS 56-85-9,非现货,按单排产,每批次随货提供 COA,可另附规格书与 MSDS。按单备货——约1周到上海。询盘请发 zhicheng1@zhicheng-bio.cn,官网不挂价,报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio,上海
- CAS 号
- 56-85-9
- 分子式
- C5H10N2O3
- 规格
- FCC
- 现货状态
- 按单排产
- 随货文件
- 批次 COA;规格书、MSDS 可索取
- 包装
- 25 kg 纸箱/袋,可按需调整
- PubChem CID
- 5961
- 报价方式
- 邮件询盘(zhicheng1@zhicheng-bio.cn),官网不展示价格
L-Glutamine
L-Glutamine 大宗原料,仅面向 B2B 生产采购——按您的目标规格供货,发货前先提供文件供质检审核。以下为指导价;发送询盘获取正式报价、起订量与交期。
价格为到上海交货指导区间,采购量越大越接近低端;原料行情每周波动,具体以询盘报价为准,通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA,下单前先过您的QA
- 可与其他SKU拼单,上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
发货前可按需安排第三方检测;产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存,现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装;FOB/CIF/DDP按航线,海运空运均可拼货。
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 56-85-9 |
|---|---|
| 分子式 | C5H10N2O3 |
| 分子量 | 146.14 |
| EINECS | 200-292-1 (PubChem also lists 230-006-0 and 105-459-1) |
| 别名 | L-Glutamine, L-Gln, Q, (2S)-2,5-diamino-5-oxopentanoic acid, levoglutamide |
| 外观 | White crystals or crystalline powder, odourless |
| 溶解性 | Water 41.3 g/L at 25 °C. Strongly temperature-dependent: one gram dissolves in 56.7 mL of water at 0 °C, 38.5 mL at 18 °C and 20.8 mL at 30 °C. Practically insoluble in methanol (3.5 mg/100 mL at 25 °C), ethanol (0.46 mg/100 mL at 23 °C), ether, benzene, acetone, ethyl acetate and chloroform. |
| 药典收载情况 | FCC (claimed grade — see note) |
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| pH (aqueous solution) | 5-6 at 14.6 g/L, 25 °C | Potentiometric |
| Ammonium | — | Per monograph |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目,表示我们没有可对外公布的固定限度:该项目在批次COA中如实报出,限度与您的质检共同确认。宁可留空,也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
Glutamine's solubility is the most temperature-sensitive of any amino acid on this list, and the numbers are worth memorising: 1 g needs 56.7 mL of water at 0 °C, 38.5 mL at 18 °C but only 20.8 mL at 30 °C. A concentrate that dissolves cleanly in a warm mixing tank can throw crystals when the pallet sits in a cold warehouse. Design your dissolution target at the coldest temperature the product will see, not at ambient.
It is practically insoluble in the usual organic solvents — 3.5 mg/100 mL in methanol, 0.46 mg/100 mL in ethanol — which rules out alcohol-based tincture and non-aqueous liquid formats entirely.
It melts with decomposition at about 185 °C, the lowest decomposition temperature of any amino acid on this list (compare leucine at 293 °C, tyrosine at 343 °C). Anything involving a hot die, a bar extruder or a spray-dry inlet needs to be checked against that ceiling rather than against a generic amino-acid assumption.
The amide side chain is the reactive part. An ammonium limit on the specification is more informative about how a batch has been stored and shipped than the assay is, because ammonia is what the amide releases when the material has been held wet or warm. Ask for it explicitly.
A 1.46% solution sits at pH 5-6, close enough to neutral that glutamine will not fight an existing beverage buffer — a real advantage over arginine base (alkaline) or citrulline malate (acidic) in a multi-ingredient pre-workout.
This is Zhicheng Bio's deepest single position at over 23 tonnes, which matters practically: glutamine is usually the highest-inclusion amino acid in a recovery formula, so it is the one where container-scale availability decides whether a launch is feasible.
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息,不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | Listed by name in FDA's food-additive regulation for amino acids as 'L-Glutamine'. That regulation permits use as a nutrient 'to significantly improve the biological quality of the total protein' of a food, subject to a cap of 12.4 (as L-glutamic acid, including L-glutamine) percent by weight of the total protein of the finished food, and to the labelling requirements in paragraph (e). It is not a general-purpose clearance for any food use, and it is not the authority under which dietary supplements are marketed — those sit under DSHEA and 21 CFR part 111. | 21 CFR 172.320(a), (b), (c)(4), (e) |
| United States (GRAS) | A search of FDA's GRAS Notice Inventory for 'glutamine' returned only an unrelated enzyme-preparation notice (GRN 1289, a protein-glutamine glutaminase). There is no GRAS notice for L-glutamine itself. | FDA GRAS Notice Inventory |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| Japan | No JP XVIII Official Monograph for L-glutamine was located. L-Glutamine appears in JP XVIII only in the Reagents/Test Solutions section, referenced to JIS K 9103 (L(+)-glutamine, Special class) — a reagent standard, not a pharmacopoeial monograph. | JP XVIII, Reagents, Test Solutions and Standard Solutions |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
相关研究文献
本化合物的同行评议文献,标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究,既不是对本原料的宣称,也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- A systematic review and meta-analysis of clinical trials in athletes assessed glutamine supplementation against body mass, lean body mass, body-fat percentage, VO2max and lymphocyte, leukocyte and neutrophil counts. Ramezani Ahmadi A, Rayyani E, Bahreini M, Mansoori A. Clin Nutr. 2019;38(3):1076-1091. PMID 29784526DOI 10.1016/j.clnu.2018.05.001原文
- A review of glutamine metabolism reported that the rate of glutamine consumption by immune cells is similar to or greater than that of glucose, and that glutamine availability is controlled mainly by key metabolic organs. Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P. Nutrients. 2018;10(11):1564. PMID 30360490DOI 10.3390/nu10111564原文
- A review of the side effects of amino acid supplements examined glutamine among other amino acids and discussed ammonia production and competition for shared membrane carriers as mechanisms relevant to high intakes. Holeček M. Physiol Res. 2022;71(1):29-45. PMID 35043647DOI 10.33549/physiolres.934790原文
包装、储存与交期
| 标准包装 | 25kg袋装、箱装或桶装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处,原包装密封保存 |
| 交期 | 按单备货——约1周到上海 |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |
