ZHICHENG BIO
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L-Citrulline Malate 2:1
2:1
¥34 – ¥38.1 /kg按采购量
01产品详情
L-Citrulline
速览
L-Citrulline —— 致诚生物供货速览
致诚生物（Zhicheng Bio）从中国上海供应L-Citrulline，CAS 372-75-8，非现货，按单排产，每批次随货提供 COA，可另附规格书与 MSDS。按单备货——约1周到上海。询盘请发 zhicheng1@zhicheng-bio.cn，官网不挂价，报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio，上海
- CAS 号
- 372-75-8
- 分子式
- C6H13N3O3
- 现货状态
- 按单排产
- 随货文件
- 批次 COA；规格书、MSDS 可索取
- 包装
- 25 kg 纸箱/袋，可按需调整
- PubChem CID
- 9750
- 报价方式
- 邮件询盘（zhicheng1@zhicheng-bio.cn），官网不展示价格
运动营养
约1周
L-Citrulline
CAS 372-75-8 · C6H13N3O3
L-Citrulline 大宗原料，仅面向 B2B 生产采购——按您的目标规格供货，发货前先提供文件供质检审核。以下为指导价；发送询盘获取正式报价、起订量与交期。
¥41 – ¥45.9 /kg
按采购量 · 到上海交货指导价
价格为到上海交货指导区间，采购量越大越接近低端；原料行情每周波动，具体以询盘报价为准，通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA，下单前先过您的QA
- 可与其他SKU拼单，上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
批次COA规格书MSDS / SDS出口文件
发货前可按需安排第三方检测；产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存，现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装；FOB/CIF/DDP按航线，海运空运均可拼货。
02标识与理化性质
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 372-75-8 |
|---|---|
| 分子式 | C6H13N3O3 |
| 分子量 | 175.19 |
| EINECS | 206-759-6 |
| 别名 | L-Citrulline, Cit, (2S)-2-amino-5-(carbamoylamino)pentanoic acid, 2-amino-5-ureidopentanoic acid |
| 外观 | White crystalline powder |
| 溶解性 | Water 200 g/L at 20 °C (also reported as 212 mg/mL) |
03规格参数
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目，表示我们没有可对外公布的固定限度：该项目在批次COA中如实报出，限度与您的质检共同确认。宁可留空，也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
04配方与处理要点
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
01
At 200 g/L in water at 20 °C, free citrulline is roughly five times more soluble than L-leucine and more than four hundred times more soluble than L-tyrosine — it is one of the easiest amino acids on this list to get into solution, and it will not be the limiting ingredient in a concentrated shot.
02
It is close to neutral in solution (reported pKa 2.43 for the carboxyl group; no strongly basic guanidino group like arginine's), so unlike arginine base it will not push the pH of a formulated drink around, and unlike citrulline malate it will not pull it down.
03
Free citrulline is 100% citrulline by definition, against 72.3% for the 2:1 malate and 56.6% for the 1:1 salt. A gram-for-gram substitution between the free amino acid and any malate grade will silently change the citrulline dose on the label.
04
Melting point is reported at 235.5 °C, and like the other amino acids here it decomposes rather than melting cleanly — keep it out of hot-melt and high-temperature extrusion steps.
05
Watch for L-ornithine and urea as the process-related impurities of interest in citrulline made by fermentation; ask for the manufacturer's limits on related substances rather than accepting a bare assay figure.
05应用领域
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
Pre-workout and nitric-oxide-precursor blends
Ready-to-drink and ready-to-mix sports beverages
Capsules and tablets
Endurance and recovery formulations
Clinical and medical nutrition blends
06各市场法规状态
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息，不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | A search of FDA's GRAS Notice Inventory for 'citrulline' returned zero records, and citrulline is not among the amino acids listed in 21 CFR 172.320. US marketing rests on DSHEA rather than on an FDA food-ingredient clearance. | FDA GRAS Notice Inventory (0 records); 21 CFR 172.320 |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
| Japan | No JP XVIII Official Monograph for this substance was located. | JP XVIII |
07相关研究文献
相关研究文献
本化合物的同行评议文献，标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究，既不是对本原料的宣称，也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- A systematic review and meta-analysis of acute citrulline supplementation reported on high-intensity strength and power outcomes across the available randomised trials. Trexler ET, Persky AM, Ryan ED, Schwartz TA, Stoner L, Smith-Ryan AE. Sports Med. 2019;49(5):707-718. PMID 30895562DOI 10.1007/s40279-019-01091-z原文
- A systematic review and meta-analysis of randomised controlled trials examined whether acute citrulline ingestion affects time-to-completion and time-to-exhaustion endurance outcomes in young healthy adults, noting that findings in this literature have been inconsistent. Harnden CS, Agu J, Gascoyne T. J Int Soc Sports Nutr. 2023;20(1):2209056. PMID 37155582DOI 10.1080/15502783.2023.2209056原文
- A review of the citrulline literature reported that oral L-citrulline and citrulline malate supplementation increase plasma citrulline and arginine concentrations along with total nitrate and nitrite concentrations. Gonzalez AM, Trexler ET. J Strength Cond Res. 2020;34(5):1480-1495. PMID 31977835DOI 10.1519/JSC.0000000000003426原文
- A systematic review and meta-analysis assessed citrulline supplementation across aerobic exercise performance outcomes including lactate, oxygen-uptake kinetics and rating of perceived exertion. Viribay A, Fernández-Landa J, Castañeda-Babarro A, Collado PS, Fernández-Lázaro D, Mielgo-Ayuso J. Nutrients. 2022;14(17):3479. PMID 36079738DOI 10.3390/nu14173479原文
08包装、储存与交期
包装、储存与交期
| 标准包装 | 25kg袋装、箱装或桶装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处，原包装密封保存 |
| 交期 | 按单备货——约1周到上海 |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |
09采购问答
采购问答
01How concentrated a citrulline solution can I make?
Free L-citrulline dissolves at 200 g/L in water at 20 °C, so a 6-8 g serving in a 60 mL shot is comfortably inside its solubility. It is rarely the ingredient that limits a concentrate.
02Free citrulline or citrulline malate for a beverage?
Free citrulline is near-neutral and gives you 100% citrulline per gram; malate is acidic and gives 72% at 2:1. If your flavour system is citrus and you want the tartness anyway, malate does double duty. If you are dosing to a citrulline number and want pH control, use the free form.
03Which impurities should I be specifying?
Ask for limits on L-ornithine, urea and total related substances, not just assay. These are the fermentation-route markers your QA will be asked about in an audit. We will request the manufacturer's own limits and put them in the specification sheet.
04How much can you ship, and how fast?
This is one of our deepest positions — around 11 tonnes available, roughly one week to Shanghai. It consolidates in the same container as citrulline malate, creatine and carnitine tartrate.
05L-Citrulline 的起订量（MOQ）是多少？
MOQ按询盘灵活确定。在询盘中告知目标数量——核心现货SKU通常小试单与多吨位大单都可承接。
06下单前能否获取 L-Citrulline 样品？
可以——样品可按需提供，用于评估与实验室验证。在询盘中说明即可，我们逐单确认安排。
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