L-Citrulline Malate 2:1 2:1
L-Citrulline Malate 2:1 —— 致诚生物供货速览
致诚生物(Zhicheng Bio)从中国上海供应L-Citrulline Malate 2:1(2:1),CAS 54940-97-5,非现货,按单排产,每批次随货提供 COA,可另附规格书与 MSDS。询盘请发 zhicheng1@zhicheng-bio.cn,官网不挂价,报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio,上海
- CAS 号
- 54940-97-5
- 分子式
- 2(C6H13N3O3)·C4H6O5
- 规格
- 2:1
- 现货状态
- 按单排产
- 随货文件
- 批次 COA;规格书、MSDS 可索取
- 包装
- 25 kg 纸箱/袋,可按需调整
- PubChem CID
- 162762
- 报价方式
- 邮件询盘(zhicheng1@zhicheng-bio.cn),官网不展示价格
L-Citrulline Malate 2:1
L-Citrulline Malate 2:1 大宗原料,仅面向 B2B 生产采购——按您的目标规格供货,发货前先提供文件供质检审核。以下为指导价;发送询盘获取正式报价、起订量与交期。
价格为到上海交货指导区间,采购量越大越接近低端;原料行情每周波动,具体以询盘报价为准,通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA,下单前先过您的QA
- 可与其他SKU拼单,上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
发货前可按需安排第三方检测;产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存,现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装;FOB/CIF/DDP按航线,海运空运均可拼货。
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 54940-97-5 (as supplied on the offer sheet) |
|---|---|
| 分子式 | 2(C6H13N3O3)·C4H6O5 |
| 分子量 | 484.47 (2:1, by summation) — PubChem gives 309.27 for the 1:1 salt |
| EINECS | 927-830-4, 812-225-9 or 976-200-5 |
| 别名 | Citrulline malate, CitMal, L-citrulline DL-malate, CM 2:1 |
| 外观 | White to off-white crystalline powder |
| 溶解性 | Freely soluble in water |
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| L-Citrulline content | — | HPLC |
| Malic acid content | — | HPLC or titration |
| Ratio (citrulline:malate) | 2:1 | Per specification |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目,表示我们没有可对外公布的固定限度:该项目在批次COA中如实报出,限度与您的质检共同确认。宁可留空,也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
The single most important thing to get right on this ingredient is the ratio, because it changes the citrulline you are actually buying. In a 2:1 composition citrulline is 72.3% of the mass; in a 1:1 salt it is 56.6%. An 8 g 'citrulline malate' dose therefore delivers either 5.8 g or 4.5 g of citrulline depending on which grade landed in the blender.
There is a CAS trap here that catches even experienced buyers. CAS 54940-97-5 corresponds to the 1:1 salt (C10H19N3O8, MW 309.27 in PubChem), yet the whole sports-nutrition trade prints it on 2:1 documentation. Write the ratio next to the CAS on your specification so an auditor cannot read the CAS as a stoichiometry claim.
Malic acid is what makes this form work in beverages: it brings sourness and a sharply lower solution pH than free citrulline, which is exactly why RTD and effervescent formats choose the malate over the free amino acid — and also why it needs a citrus or berry flavour system rather than a creamy one.
The malate load has to be counted in your total acid budget. At an 8 g dose the 2:1 grade contributes roughly 2.2 g of malic acid, which is enough to move the pH and titratable acidity of an unbuffered drink on its own.
The malic acid in commercial citrulline malate is usually DL-malic acid, not L-malic. If your label, your organic certification or your destination market cares about that distinction, ask for it in writing — it is rarely stated unless requested.
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息,不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | A search of FDA's GRAS Notice Inventory for 'citrulline' returned zero records — there is no GRAS notice for L-citrulline or citrulline malate. Citrulline is also not among the amino acids listed in 21 CFR 172.320. US marketing therefore rests on dietary supplement law (DSHEA) rather than on any FDA food-ingredient clearance. | FDA GRAS Notice Inventory (0 records for 'citrulline'); 21 CFR 172.320 |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
| Japan | No JP XVIII Official Monograph for this substance was located. | JP XVIII |
相关研究文献
本化合物的同行评议文献,标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究,既不是对本原料的宣称,也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- A critical review of citrulline malate and exercise performance noted that a single acute 8 g dose has been the most common protocol and that results across resistance-exercise and cycling studies have been equivocal. Gough LA, Sparks SA, McNaughton LR, Higgins MF, Newbury JW, Trexler E, Faghy MA, Bridge CA. Eur J Appl Physiol. 2021;121(12):3283-3295. PMID 34417881DOI 10.1007/s00421-021-04774-6原文
- A meta-analysis of four randomised controlled trials (138 assessments) in resistance-trained adults did not observe an overall effect of citrulline malate supplementation favouring citrulline malate on muscle strength outcomes. Aguiar AF, Casonatto J. J Diet Suppl. 2022;19(6):772-790. PMID 34176406DOI 10.1080/19390211.2021.1939473原文
- A six-week double-blind placebo-controlled trial in 33 resistance-trained men compared 8 g/day L-citrulline with 12 g/day L-citrulline DL-malate and placebo, and reported significant differences from placebo for total upper-body repetitions to failure in both active arms. Bayat D, Azizi M, Behpour N, Tinsley GM. J Int Soc Sports Nutr. 2025;22(1):2513944. PMID 40470618DOI 10.1080/15502783.2025.2513944原文
- A systematic review and three-level meta-analysis examined the effects of citrulline malate supplementation across exercise-performance outcomes. Wang X, Fan X, Chang J, et al. Nutrients. 2026;18(12):1881. PMID 42356270DOI 10.3390/nu18121881原文
包装、储存与交期
| 标准包装 | 25kg袋装、箱装或桶装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处,原包装密封保存 |
| 交期 | undefined |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |
