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L-Carnitine HCl

速览

L-Carnitine HCl —— 致诚生物供货速览

致诚生物(Zhicheng Bio)从中国上海供应L-Carnitine HCl,CAS 6645-46-1,非现货,按单排产,每批次随货提供 COA,可另附规格书与 MSDS。按单备货——约1周到上海。询盘请发 zhicheng1@zhicheng-bio.cn,官网不挂价,报价按数量与交货条款单独出。

供应商
致诚生物 Zhicheng Bio,上海
CAS 号
6645-46-1
分子式
C7H15NO3·HCl
现货状态
按单排产
随货文件
批次 COA;规格书、MSDS 可索取
包装
25 kg 纸箱/袋,可按需调整
PubChem CID
656657
报价方式
邮件询盘(zhicheng1@zhicheng-bio.cn),官网不展示价格
肉碱系列 约1周

L-Carnitine HCl

CAS 6645-46-1 · C7H15NO3·HCl

L-Carnitine HCl 大宗原料,仅面向 B2B 生产采购——按您的目标规格供货,发货前先提供文件供质检审核。以下为指导价;发送询盘获取正式报价、起订量与交期。

¥225 – ¥252 /kg 按采购量 · 到上海交货指导价

价格为到上海交货指导区间,采购量越大越接近低端;原料行情每周波动,具体以询盘报价为准,通常 1 个工作日内回复。

类别: 肉碱系列
供货状态: 按单备货——约1周到上海
包装: 25 kg 袋装、箱装或桶装(标准)

供应要点

  • 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
  • 报价即附近期批次COA,下单前先过您的QA
  • 可与其他SKU拼单,上海一票发运
  • 发货前可按需安排第三方检测

每批随附文件

批次COA规格书MSDS / SDS出口文件

发货前可按需安排第三方检测;产地证、非转基因或过敏原声明可按目的地市场要求另行安排。

运费与交期

估算本品运费

约1周按单备货——约1周到上海
空运
运输时效
预估运费(USD)*
全程时间
海运拼箱
运输时效
预估运费(USD)*
全程时间

文件先行

每批附COA、规格书与MSDS——发货前即可交由您的QA审核。

现货储备

核心品类多吨位库存,现货SKU上海即刻发运。

认证供应链

货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。

灵活出口

25kg袋/箱/桶装;FOB/CIF/DDP按航线,海运空运均可拼货。

02标识与理化性质

标识与理化性质

本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。

CAS 号6645-46-1
分子式C7H16ClNO3 (written as C7H15NO3·HCl)
分子量197.66
EINECS229-663-6
别名Levocarnitine hydrochloride, L-Carnitine HCl, (R)-carnitine hydrochloride, vitamin BT hydrochloride
外观White crystalline powder
溶解性Freely soluble in water
03规格参数

规格参数

下表为典型参数——以随报价发送的规格书与批次COA为准。

项目规格检测方法
L-Carnitine content (free base equivalent)81.6% theoreticalCalculated from molecular weights
Assay (as-is / dried basis)Titration or HPLC per the applicable monograph
AppearanceVisual
IdentificationIR / specific optical rotation per monograph
Specific optical rotationPolarimetry
Loss on dryingGravimetric
Residue on ignition / sulphated ashGravimetric
ChloridePer monograph
SulphatePer monograph
IronPer monograph
Other amino acids / related substancesTLC or HPLC per monograph
Heavy metals (Pb / As / Cd / Hg)ICP-MS or per monograph
Microbiology (TAMC / TYMC / E. coli / Salmonella)USP <61>/<62> or equivalent

表中显示「—」的项目,表示我们没有可对外公布的固定限度:该项目在批次COA中如实报出,限度与您的质检共同确认。宁可留空,也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。

04配方与处理要点

配方与处理要点

我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。

01

The reason salts of carnitine exist at all is moisture: carnitine free base is so hygroscopic that it is impractical as a dry powder, which is why the trade sells the hydrochloride and the L-tartrate. Between the two salts, the HCl is the higher-potency one at 81.6% carnitine (161.20/197.66) versus 68% for the tartrate.

02

The HCl salt makes an acidic solution, so it fits naturally into low-pH beverages and shots but will shift the pH of an unbuffered blend downward — the opposite direction from the tartrate at equal carnitine load.

03

Chloride load matters in two places: a chloride-sensitive analytical method (the chloride limit test in an amino-acid monograph) and stainless-steel process equipment held wet. Both are non-issues with the tartrate.

04

Because it is the highest-potency carnitine salt on this list, it is the one to use when the label needs a high carnitine number in a small capsule — 500 mg carnitine needs about 613 mg of the HCl versus about 735 mg of the tartrate.

05

Any switch between carnitine salt forms must be recalculated on the free-base equivalent, and the counter-ion (chloride versus tartrate) has to be declared correctly in the ingredient statement.

05应用领域

应用领域

仅面向B2B生产用途——不作任何成品或功效宣称。

Sports-nutrition and weight-management powders and capsules
Liquid shots and ready-to-drink formats
Infant and clinical nutrition (subject to the destination market's own rules)
Effervescent and instant-drink powders
Veterinary and pet nutrition premixes
06各市场法规状态

各市场法规状态

以资料允许的最保守口径陈述原料的法规状态。这是供应链信息,不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。

市场状态依据
United StatesL-carnitine is not one of the amino acids listed in FDA's amino-acid food-additive regulation (21 CFR 172.320) — that list does not include carnitine in any form. Two GRAS notices for levocarnitine/L-carnitine-L-tartrate were withdrawn at the notifier's request (GRN 362 in 2011, GRN 935 in 2020); GRN 993 for L-carnitine-L-tartrate closed with 'FDA has no questions' in 2021 but for infant formula only. Dietary supplement use rests on DSHEA, not on any of these.21 CFR 172.320; FDA GRAS Notice Inventory GRN 362, 935, 993
European UnionAmino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice.Directive 2002/46/EC (food supplements); national member-state rules
ChinaStatus as a nutrient fortification substance / food additive under Chinese national standards to be confirmed.GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements
JapanNo JP XVIII Official Monograph for this substance was located.JP XVIII
07相关研究文献

相关研究文献

本化合物的同行评议文献,标识号均可点击直达原文——不必只听我们说。

以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究,既不是对本原料的宣称,也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。

  1. A pharmacokinetic review reported that after oral doses of 1-6 g the absolute bioavailability of L-carnitine is 5-18%, whereas the bioavailability of dietary L-carnitine may be as high as 75%. Evans AM, Fornasini G. Clin Pharmacokinet. 2003;42(11):941-967. PMID 12908852DOI 10.2165/00003088-200342110-00002原文
  2. A review of carnitine kinetics reported bioavailability of dietary L-carnitine at 54-87%, absorption of 0.5-6 g supplemental doses as primarily passive with 14-18% bioavailability, and a whole-body turnover time of 38-119 hours at normal dietary intake. Rebouche CJ. Ann N Y Acad Sci. 2004;1033:30-41. PMID 15591001DOI 10.1196/annals.1320.003原文
  3. A systematic review of oral L-carnitine supplementation grouped trials by exercise intensity and examined which doses and timings had been used across the moderate- and high-intensity literature. Mielgo-Ayuso J, Pietrantonio L, Viribay A, Calleja-González J, González-Bernal J, Fernández-Lázaro D. Nutrients. 2021;13(12):4359. PMID 34959912DOI 10.3390/nu13124359原文
08包装、储存与交期

包装、储存与交期

标准包装25kg袋装、箱装或桶装
定制包装长期客户可安排定制包装与标签
储存条件阴凉干燥处,原包装密封保存
交期按单备货——约1周到上海
运输上海海运/空运拼货 · FOB/CIF/DDP按航线
09采购问答

采购问答

01HCl or tartrate — which carnitine salt should I order?
Potency versus pH. The HCl is 81.6% carnitine and gives an acidic solution; the tartrate is 68% carnitine and is the form the trade treats as non-hygroscopic for dry blends. High-potency capsules lean HCl; flavoured powders and stick packs usually lean tartrate.
02How much HCl salt do I need for a 500 mg carnitine claim?
About 613 mg, from the 81.6% free-base equivalent. Always state on your RFQ whether your target is carnitine or salt weight — most disputes on carnitine orders come from that one ambiguity.
03Is D-carnitine controlled in this material?
It should be. Only the L (R) enantiomer is the physiological form, and D-carnitine is the impurity buyers care about. Ask us for the manufacturer's enantiomeric purity limit and the method used, and we will put it in the specification sheet before you order.
04Lead time and quantity for this SKU?
This is a smaller-holding item than the tartrate — around 50 kg on hand with roughly one week to Shanghai for anything larger. If you need tonnage carnitine now, the tartrate is where our depth is.
05L-Carnitine HCl 的起订量(MOQ)是多少?
MOQ按询盘灵活确定。在询盘中告知目标数量——核心现货SKU通常小试单与多吨位大单都可承接。
06下单前能否获取 L-Carnitine HCl 样品?
可以——样品可按需提供,用于评估与实验室验证。在询盘中说明即可,我们逐单确认安排。
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