ZHICHENG BIO
肉碱系列约1周
L-Carnitine HCl
¥225 – ¥252 /kg按采购量
01产品详情
Acetyl-L-Carnitine HCl
速览
Acetyl-L-Carnitine HCl —— 致诚生物供货速览
致诚生物（Zhicheng Bio）从中国上海供应Acetyl-L-Carnitine HCl，CAS 5080-50-2，非现货，按单排产，每批次随货提供 COA，可另附规格书与 MSDS。按单备货——约1周到上海。询盘请发 zhicheng1@zhicheng-bio.cn，官网不挂价，报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio，上海
- CAS 号
- 5080-50-2
- 分子式
- C9H17NO4·HCl
- 现货状态
- 按单排产
- 随货文件
- 批次 COA；规格书、MSDS 可索取
- 包装
- 25 kg 纸箱/袋，可按需调整
- PubChem CID
- 2733928
- 报价方式
- 邮件询盘（zhicheng1@zhicheng-bio.cn），官网不展示价格
肉碱系列
约1周
Acetyl-L-Carnitine HCl
CAS 5080-50-2 · C9H17NO4·HCl
Acetyl-L-Carnitine HCl 大宗原料，仅面向 B2B 生产采购——按您的目标规格供货，发货前先提供文件供质检审核。以下为指导价；发送询盘获取正式报价、起订量与交期。
¥185 – ¥207.2 /kg
按采购量 · 到上海交货指导价
价格为到上海交货指导区间，采购量越大越接近低端；原料行情每周波动，具体以询盘报价为准，通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA，下单前先过您的QA
- 可与其他SKU拼单，上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
批次COA规格书MSDS / SDS出口文件
发货前可按需安排第三方检测；产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存，现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装；FOB/CIF/DDP按航线，海运空运均可拼货。
02标识与理化性质
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 5080-50-2 |
|---|---|
| 分子式 | C9H18ClNO4 (written as C9H17NO4·HCl) |
| 分子量 | 239.69 |
| EINECS | 610-570-8 |
| 别名 | ALCAR, ALC, Acetylcarnitine hydrochloride, Levacecarnine hydrochloride, O-acetyl-L-carnitine hydrochloride |
| 外观 | White crystalline powder |
| 溶解性 | Freely soluble in water; hygroscopic |
03规格参数
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| Acetyl-L-carnitine content (free base equivalent) | 84.8% theoretical | Calculated from molecular weights |
| Free L-carnitine (hydrolysis product) | — | HPLC |
| Water content | — | Karl Fischer |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目，表示我们没有可对外公布的固定限度：该项目在批次COA中如实报出，限度与您的质检共同确认。宁可留空，也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
04配方与处理要点
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
01
ALCAR is an ester, and that changes everything about how you handle it relative to plain carnitine. The acetyl group hydrolyses back to free L-carnitine and acetic acid, so free carnitine on the COA is the row that tells you whether a lot has been held warm or wet. Ask for it — a bare 'assay ≥98%' does not answer the question.
02
Because it hydrolyses, aqueous liquid formats are the hard case and dry capsules or tablets are the easy one. If a customer asks for ALCAR in a ready-to-drink product, the conversation should start with hold time, pH and temperature, not with solubility.
03
It is markedly hygroscopic, more so than the carnitine tartrate. That makes Karl Fischer water the right control rather than loss on drying (which cannot separate water from volatile acetic acid), and it makes low-humidity dispensing a requirement rather than good practice.
04
Potency is 84.8% acetyl-L-carnitine as the free base in the hydrochloride (203.24/239.69). Note the trap: the carnitine equivalent is lower again, 67.3%, because the acetyl group is part of the mass. A label that declares 'L-carnitine' from an ALCAR raw material has to be calculated on the right basis.
05
The hydrochloride counter-ion gives an acidic solution, which slows ester hydrolysis relative to neutral or alkaline conditions — the reason the material is sold as the HCl salt rather than the free base.
06
At roughly five times the price per kilogram of L-carnitine tartrate, ALCAR is not a drop-in substitute on cost. It is specified when the acetyl form is the point of the formulation, not as a carnitine source.
05应用领域
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
Cognitive-support and nootropic formulations
Sports-nutrition and energy formulations
Capsules and tablets (the dominant format, for hygroscopicity reasons)
Nutraceutical combination products
Veterinary and companion-animal nutrition
06各市场法规状态
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息，不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | Acetyl-L-carnitine is not among the amino acids listed in 21 CFR 172.320, and no GRAS notice for acetyl-L-carnitine was found in FDA's GRAS Notice Inventory (a 'carnitine' search returned only GRN 362, 935 and 993, all for levocarnitine or L-carnitine-L-tartrate). US supplement marketing rests on DSHEA. | 21 CFR 172.320; FDA GRAS Notice Inventory ('carnitine' search) |
| European Union | Acetyl-L-carnitine is a prescription medicine in some EU member states, which can constrain or prohibit its use as a food supplement ingredient in those markets. | National medicines classification; Directive 2001/83/EC borderline assessment |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
| Japan | No JP XVIII Official Monograph for this substance was located. | JP XVIII |
07相关研究文献
相关研究文献
本化合物的同行评议文献，标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究，既不是对本原料的宣称，也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- A Cochrane systematic review of double-blind randomised trials of acetyl-L-carnitine in dementia reported that early studies suggested a beneficial effect on cognition and behaviour in ageing subjects while later, larger studies did not support those findings, and that the efficacy of acetyl-L-carnitine in cognitive decline remained unclear. Hudson S, Tabet N. Cochrane Database Syst Rev. 2003;2003(2):CD003158. PMID 12804452DOI 10.1002/14651858.CD003158原文
- A Cochrane review of acetyl-L-carnitine for hepatic encephalopathy identified five randomised clinical trials involving 398 participants, all conducted in Italy by a single team, and assessed all of them as at high risk of bias and underpowered. Martí-Carvajal AJ, Gluud C, Arevalo-Rodriguez I, Martí-Amarista CE. Cochrane Database Syst Rev. 2019;1(1):CD011451. PMID 30610762DOI 10.1002/14651858.CD011451.pub2原文
- In a double-blind randomised placebo-controlled proof-of-principle trial, adults with severe carpal tunnel syndrome received 3000 mg/day oral acetyl-L-carnitine or placebo for two months after carpal tunnel release, with outcomes assessed to 12 months post-operatively. Curran MWT, Morhart MJ, Olson JL, Hachisuka A, Chan KM. Plast Reconstr Surg. 2019;143(1):111e-120e. PMID 30589790DOI 10.1097/PRS.0000000000005089原文
- A review of carnitine kinetics reported that in vitro experiments suggest acetyl-L-carnitine is partially hydrolysed in enterocytes during absorption, and that circulating acetyl-L-carnitine concentration increased 43% after oral supplements of 2 g/day, indicating that it is absorbed at least partially without hydrolysis. Rebouche CJ. Ann N Y Acad Sci. 2004;1033:30-41. PMID 15591001DOI 10.1196/annals.1320.003原文
08包装、储存与交期
包装、储存与交期
| 标准包装 | 25kg袋装、箱装或桶装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处，原包装密封保存 |
| 交期 | 按单备货——约1周到上海 |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |
09采购问答
采购问答
01What should I look at on an ALCAR COA besides assay?
Free L-carnitine and Karl Fischer water. ALCAR is an ester that hydrolyses back to carnitine and acetic acid, so free carnitine is the number that tells you how a batch has been stored and shipped. Loss on drying is not good enough because it cannot separate water from volatile acetic acid.
02Can I use ALCAR in a liquid product?
It is the hard case. The acetyl ester hydrolyses in water, faster at higher pH and higher temperature. If you need a liquid, come to us with your pH, fill temperature and intended shelf life and we will discuss it with the manufacturer before you commit to a formulation.
03How do I convert ALCAR HCl to a carnitine label figure?
Carefully, and on the right basis. Acetyl-L-carnitine free base is 84.8% of the hydrochloride (203.24/239.69); L-carnitine equivalent is lower again at about 67.3% because the acetyl group is part of the mass. State on your RFQ which basis your target is on.
04Why is it so much more expensive than carnitine tartrate?
It is a different molecule with an extra synthesis step, not a grade of carnitine. At roughly five times the tartrate's price per kilogram it is specified when the acetyl form is the point of the product. If your formula just needs carnitine, the tartrate is the value route and we hold 12 tonnes of it.
05Can we sell an ALCAR supplement in the EU?
Check country by country before you commit. Acetyl-L-carnitine is a prescription medicine in some EU member states, which can rule it out as a supplement ingredient there. This is a regulatory question for your own counsel; we will supply whatever documentation the manufacturer can provide to support it.
06Acetyl-L-Carnitine HCl 的起订量（MOQ）是多少？
MOQ按询盘灵活确定。在询盘中告知目标数量——核心现货SKU通常小试单与多吨位大单都可承接。
07下单前能否获取 Acetyl-L-Carnitine HCl 样品？
可以——样品可按需提供，用于评估与实验室验证。在询盘中说明即可，我们逐单确认安排。
10相关产品
您可能还需要
肉碱系列约1周
L-Carnitine Tartrate
68% L-Carnitine / 32% L-Tartaric Acid
¥160 – ¥179.2 /kg按采购量
氨基酸undefined
L-Arginine Base
USP32
¥22 – ¥24.6 /kg按采购量