ZHICHENG BIO
氨基酸undefined
L-Arginine Base
USP32
¥22 – ¥24.6 /kg按采购量
01产品详情
L-Phenylalanine
速览
L-Phenylalanine —— 致诚生物供货速览
致诚生物（Zhicheng Bio）从中国上海供应L-Phenylalanine，CAS 63-91-2，非现货，按单排产，每批次随货提供 COA，可另附规格书与 MSDS。询盘请发 zhicheng1@zhicheng-bio.cn，官网不挂价，报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio，上海
- CAS 号
- 63-91-2
- 分子式
- C9H11NO2
- 现货状态
- 按单排产
- 随货文件
- 批次 COA；规格书、MSDS 可索取
- 包装
- Bags
- PubChem CID
- 6140
- 报价方式
- 邮件询盘（zhicheng1@zhicheng-bio.cn），官网不展示价格
氨基酸
undefined
L-Phenylalanine
CAS 63-91-2 · C9H11NO2
L-Phenylalanine 大宗原料，仅面向 B2B 生产采购——按您的目标规格供货，发货前先提供文件供质检审核。以下为指导价；发送询盘获取正式报价、起订量与交期。
¥36.5 – ¥40.9 /kg
按采购量 · 到上海交货指导价
价格为到上海交货指导区间，采购量越大越接近低端；原料行情每周波动，具体以询盘报价为准，通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA，下单前先过您的QA
- 可与其他SKU拼单，上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
批次COA规格书MSDS / SDS出口文件
发货前可按需安排第三方检测；产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存，现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装；FOB/CIF/DDP按航线，海运空运均可拼货。
02标识与理化性质
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 63-91-2 |
|---|---|
| 分子式 | C9H11NO2 |
| 分子量 | 165.19 |
| EINECS | 200-568-1 |
| 别名 | L-Phenylalanine, L-Phe, F, (2S)-2-amino-3-phenylpropanoic acid |
| 外观 | Odourless white crystalline powder or colourless plate-like crystals, slightly bitter taste |
| 溶解性 | Water 26.9 g/L at 25 °C (Merck series: 19.8 g/L at 0 °C rising to 99.0 g/L at 100 °C). Very slightly soluble in methanol and ethanol; insoluble in ethyl ether and benzene. Sublimes in vacuo. |
| 药典收载情况 | FCC · JP |
03规格参数
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| pH (1% aqueous solution) | 5.4-6.0 | Potentiometric |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目，表示我们没有可对外公布的固定限度：该项目在批次COA中如实报出，限度与您的质检共同确认。宁可留空，也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
04配方与处理要点
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
01
Phenylalanine is the one product on this list with a real consumer-safety labelling dimension: it is the amino acid people with phenylketonuria must restrict, which is why aspartame-containing foods carry a phenylalanine warning. Any finished product built on free L-phenylalanine should have its warning statement decided by a regulatory reviewer, not copied from a competitor.
02
Water solubility of 26.9 g/L at 25 °C is modest — comparable to leucine — but the temperature dependence is the steepest on this list: 19.8 g/L at 0 °C to 99.0 g/L at 100 °C, a five-fold swing. Hot-mix headroom is large and cold-storage precipitation risk is correspondingly real.
03
It sublimes in vacuo. That matters for anyone freeze-drying or vacuum-drying a phenylalanine-containing solution — you can lose active to the condenser rather than to degradation, and mass balance will not close.
04
The aromatic ring gives it UV absorbance, which is convenient analytically (it is why phenylalanine, tyrosine and tryptophan are the amino acids you can see on a plain UV detector) and inconvenient if you are running a UV assay on a multi-ingredient blend where it will interfere.
05
A 1% solution is pH 5.4-6.0 and the taste is described as slightly bitter — mild enough that phenylalanine is not usually the flavour problem in an EAA blend, unlike isoleucine or leucine.
06
Free L-phenylalanine and the aspartame supply chain draw on the same fermentation capacity, so pricing on this SKU tracks sweetener demand more than sports-nutrition demand.
05应用领域
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
Free-form amino acid and EAA blends
Mood and focus supplement formulations
Aspartame and sweetener manufacturing intermediate (a very large industrial outlet)
Clinical and enteral nutrition
Capsules and tablets
Cell-culture media
06各市场法规状态
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息，不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | Listed by name in FDA's food-additive regulation for amino acids as 'L-Phenylalanine'. That regulation permits use as a nutrient 'to significantly improve the biological quality of the total protein' of a food, subject to a cap of 5.8 percent by weight of the total protein of the finished food, and to the labelling requirements in paragraph (e). It is not a general-purpose clearance for any food use, and it is not the authority under which dietary supplements are marketed — those sit under DSHEA and 21 CFR part 111. | 21 CFR 172.320(a), (b), (c)(4), (e) |
| United States (labelling) | Products containing phenylalanine sold in the US and many other markets carry a phenylketonuria warning; aspartame-containing foods are the familiar case. Whether and how this applies to a free L-phenylalanine ingredient in your finished product is a labelling question for your regulatory counsel. | US food labelling practice for phenylalanine-containing products |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| Japan | An Official Monograph titled 'L-Phenylalanine' is listed in the Japanese Pharmacopoeia, Eighteenth Edition. Monograph existence only — no limits transcribed. | JP XVIII, Official Monographs |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
07相关研究文献
相关研究文献
本化合物的同行评议文献，标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究，既不是对本原料的宣称，也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- A Cochrane systematic review assessed the effects of a low-phenylalanine diet commenced early in life in people with phenylketonuria, and the effects of relaxing or terminating the diet on intelligence, neuropsychological outcomes, growth and quality of life. Jameson E, Remmington T. Cochrane Database Syst Rev. 2020;7(7):CD001304. PMID 32672365DOI 10.1002/14651858.CD001304.pub3原文
- A review of amino acid supplement side effects examined individual amino acids including their competition with other amino acids for shared membrane carriers and for the enzymes responsible for their degradation. Holeček M. Physiol Res. 2022;71(1):29-45. PMID 35043647DOI 10.33549/physiolres.934790原文
08包装、储存与交期
包装、储存与交期
| 标准包装 | 袋装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处，原包装密封保存 |
| 交期 | undefined |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |
09采购问答
采购问答
01Do I need a phenylketonuria warning on my product?
Very possibly, and this is not a question to answer from a supplier's web page. Phenylalanine is the amino acid PKU patients must restrict, which is why aspartame products carry a warning. Get the requirement for each destination market confirmed by your regulatory reviewer before you print cartons.
02How much can I dissolve, and does temperature help?
26.9 g/L in water at 25 °C, but the temperature curve is the steepest of any amino acid we stock — 19.8 g/L at 0 °C up to 99.0 g/L at 100 °C. Hot mixing gives you a lot of headroom, and a cold warehouse takes it straight back. Design to your minimum storage temperature.
03We freeze-dry our premix. Anything to watch?
Yes — phenylalanine sublimes in vacuo. If your mass balance does not close after lyophilisation, check the condenser before you suspect degradation.
04Is this the same grade used for aspartame production?
Not necessarily, and it is worth asking. Aspartame-intermediate phenylalanine is a huge market with its own specifications. Tell us your monograph and application in the RFQ and we will confirm which plant and grade the offer is against.
05L-Phenylalanine 的起订量（MOQ）是多少？
MOQ按询盘灵活确定。在询盘中告知目标数量——核心现货SKU通常小试单与多吨位大单都可承接。
06下单前能否获取 L-Phenylalanine 样品？
可以——样品可按需提供，用于评估与实验室验证。在询盘中说明即可，我们逐单确认安排。
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