ZHICHENG BIO
氨基酸约1周
L-Glutamine
FCC
¥53.5 – ¥59.9 /kg按采购量
01产品详情
L-Arginine Base USP32
速览
L-Arginine Base —— 致诚生物供货速览
致诚生物（Zhicheng Bio）从中国上海供应L-Arginine Base（USP32），CAS 74-79-3，非现货，按单排产，每批次随货提供 COA，可另附规格书与 MSDS。询盘请发 zhicheng1@zhicheng-bio.cn，官网不挂价，报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio，上海
- CAS 号
- 74-79-3
- 分子式
- C6H14N4O2
- 规格
- USP32
- 现货状态
- 按单排产
- 随货文件
- 批次 COA；规格书、MSDS 可索取
- 包装
- 25 kg 纸箱/袋，可按需调整
- PubChem CID
- 6322
- 报价方式
- 邮件询盘（zhicheng1@zhicheng-bio.cn），官网不展示价格
氨基酸
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L-Arginine Base
USP32
CAS 74-79-3 · C6H14N4O2
L-Arginine Base 大宗原料，仅面向 B2B 生产采购——按您的目标规格供货，发货前先提供文件供质检审核。以下为指导价；发送询盘获取正式报价、起订量与交期。
¥22 – ¥24.6 /kg
按采购量 · 到上海交货指导价
价格为到上海交货指导区间，采购量越大越接近低端；原料行情每周波动，具体以询盘报价为准，通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA，下单前先过您的QA
- 可与其他SKU拼单，上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
批次COA规格书MSDS / SDS出口文件
发货前可按需安排第三方检测；产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存，现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装；FOB/CIF/DDP按航线，海运空运均可拼货。
02标识与理化性质
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 74-79-3 |
|---|---|
| 分子式 | C6H14N4O2 |
| 分子量 | 174.20 |
| EINECS | 200-811-1 |
| 别名 | L-Arginine, L-Arg, (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid, Arginine base, free-base arginine |
| 外观 | White crystals or crystalline powder, odourless |
| 溶解性 | Water 182 g/L at 25 °C; slightly soluble in ethanol; insoluble in diethyl ether. The saturated aqueous solution contains about 15% w/w at 21 °C. |
| 药典收载情况 | FCC · JP (as L-Arginine Hydrochloride) |
03规格参数
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目，表示我们没有可对外公布的固定限度：该项目在批次COA中如实报出，限度与您的质检共同确认。宁可留空，也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
04配方与处理要点
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
01
Arginine base is strongly alkaline in solution — the Merck Index describes the aqueous solution as 'strongly alkaline' and gives pK3 = 13.2 for the guanidino group (pK1 2.18, pK2 9.09). In a beverage or an effervescent stick pack it will move system pH upward on its own; this is the practical reason formulators reach for arginine HCl instead when they need a near-neutral solution.
02
The base absorbs carbon dioxide from air. The Merck Index record notes that aqueous solutions absorb CO2 from the air, which slowly forms carbonate and drifts solution pH and titratable assay. Keep drums sealed and avoid holding open solutions.
03
Aqueous solubility is high — 182 g/L at 25 °C — but the saturated solution is only about 15% w/w at 21 °C, so a 1500 mg/serving RTD is easy while a high-load concentrate is not.
04
It decomposes rather than melting cleanly (browns around 230 °C, decomposes at 244 °C), so it is unsuitable for hot-melt or high-temperature extrusion steps.
05
'Base' versus 'HCl' is a potency question, not a quality question: the base is 100% arginine while the monohydrochloride is 82.7% arginine by stoichiometry (174.20/210.66). A formula switching between them must be re-balanced or the label arginine figure will be wrong.
05应用领域
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
Pre-workout and pump/vasodilator powder blends
Sports-nutrition capsules and tablets
Amino acid blends and free-form EAA products
Nutritional and clinical nutrition formulations
Cosmetic formulations where a basic amino acid is used as a pH adjuster
Buffer and cell-culture media preparation
06各市场法规状态
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息，不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | Listed by name in FDA's food-additive regulation for amino acids as 'L-Arginine'. That regulation permits use as a nutrient 'to significantly improve the biological quality of the total protein' of a food, subject to a cap of 6.6 percent by weight of the total protein of the finished food, and to the labelling requirements in paragraph (e). It is not a general-purpose clearance for any food use, and it is not the authority under which dietary supplements are marketed — those sit under DSHEA and 21 CFR part 111. | 21 CFR 172.320(a), (b), (c)(4), (e) |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| Japan | An Official Monograph titled 'L-Arginine Hydrochloride' is listed in the Japanese Pharmacopoeia, Eighteenth Edition. Monograph existence only — no limits transcribed. | JP XVIII, Official Monographs |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
07相关研究文献
相关研究文献
本化合物的同行评议文献，标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究，既不是对本原料的宣称，也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- In a crossover study in ten healthy volunteers, the absolute bioavailability of a single 10 g oral dose of L-arginine was reported to be approximately 20%, with a peak plasma concentration of 50.0 ± 13.4 µg/mL one hour after dosing. Tangphao O, Grossmann M, Chalon S, Hoffman BB, Blaschke TF. Br J Clin Pharmacol. 1999;47(3):261-266. PMID 10215749DOI 10.1046/j.1365-2125.1999.00883.x原文
- A randomised placebo-controlled study in seventeen healthy men reported no significant change in plasma nitrite plus nitrate after a single 6 g oral dose of L-arginine hydrochloride over 120 minutes. Alvares TS, Conte-Junior CA, Silva JT, Paschoalin VM. Nutr Metab (Lond). 2012;9(1):54. PMID 22691607DOI 10.1186/1743-7075-9-54原文
- A review of nitric-oxide precursor ingredients used in strength-performance supplements described the NOS-dependent and nitrate-nitrite-NO pathways and positioned L-citrulline as an effective precursor of L-arginine. Gonzalez AM, Townsend JR, Pinzone AG, Hoffman JR. Nutrients. 2023;15(3):660. PMID 36771366DOI 10.3390/nu15030660原文
08包装、储存与交期
包装、储存与交期
| 标准包装 | 25kg袋装、箱装或桶装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处，原包装密封保存 |
| 交期 | undefined |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |
09采购问答
采购问答
01The listing says USP32 — is that still a current specification?
USP 32 is a superseded edition of the United States Pharmacopeia. In practice 'USP32' on an Asian amino-acid offer sheet means the material is made to the arginine monograph as it stood in that edition. If your QA needs compliance with the current USP-NF, say so in the RFQ and we will get the manufacturer to confirm against the edition you name, in writing, before shipment.
02Should I buy the base or the hydrochloride?
Take the base when you want maximum arginine per kilogram and the alkalinity is acceptable — capsules, tablets, dry blends. Take the hydrochloride when you need a solution near neutral pH or a less hygroscopic feel in a flavoured powder. The base is 100% arginine; the HCl salt is 82.7% arginine by molecular weight, so the two are not drop-in substitutes on a label.
03Will arginine base raise the pH of my drink?
Yes. Its aqueous solution is strongly alkaline (the guanidino group has a pK around 13). Expect to re-titrate an acidic beverage after adding it, and expect the free base to pick up CO2 from air if solutions are held open.
04How is it packed and how should we store it?
Standard 25 kg bags, cartons or drums out of Shanghai. Because the free base takes up CO2 from the air, keep drums closed and decant under low humidity; do not leave part-used containers open on the line overnight.
05L-Arginine Base 的起订量（MOQ）是多少？
MOQ按询盘灵活确定。在询盘中告知目标数量——核心现货SKU通常小试单与多吨位大单都可承接。
06下单前能否获取 L-Arginine Base 样品？
可以——样品可按需提供，用于评估与实验室验证。在询盘中说明即可，我们逐单确认安排。
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