L-Arginine HCl 83% Arginine
L-Arginine HCl —— 致诚生物供货速览
致诚生物(Zhicheng Bio)从中国上海供应L-Arginine HCl(83% Arginine),CAS 1119-34-2,非现货,按单排产,每批次随货提供 COA,可另附规格书与 MSDS。询盘请发 zhicheng1@zhicheng-bio.cn,官网不挂价,报价按数量与交货条款单独出。
- 供应商
- 致诚生物 Zhicheng Bio,上海
- CAS 号
- 1119-34-2
- 分子式
- C6H14N4O2·HCl
- 规格
- 83% Arginine
- 现货状态
- 按单排产
- 随货文件
- 批次 COA;规格书、MSDS 可索取
- 包装
- 25 kg 纸箱/袋,可按需调整
- PubChem CID
- 66250
- 报价方式
- 邮件询盘(zhicheng1@zhicheng-bio.cn),官网不展示价格
L-Arginine HCl
L-Arginine HCl 大宗原料,仅面向 B2B 生产采购——按您的目标规格供货,发货前先提供文件供质检审核。以下为指导价;发送询盘获取正式报价、起订量与交期。
价格为到上海交货指导区间,采购量越大越接近低端;原料行情每周波动,具体以询盘报价为准,通常 1 个工作日内回复。
供应要点
- 按您的目标规格供货——适用时对标 USP / FCC / JP 药典
- 报价即附近期批次COA,下单前先过您的QA
- 可与其他SKU拼单,上海一票发运
- 发货前可按需安排第三方检测
每批随附文件
发货前可按需安排第三方检测;产地证、非转基因或过敏原声明可按目的地市场要求另行安排。
文件先行
每批附COA、规格书与MSDS——发货前即可交由您的QA审核。
现货储备
核心品类多吨位库存,现货SKU上海即刻发运。
认证供应链
货源来自经审核的认证工厂——ISO、HACCP、Halal与Kosher可提供。
灵活出口
25kg袋/箱/桶装;FOB/CIF/DDP按航线,海运空运均可拼货。
标识与理化性质
本品的化合物标识与理化性质。以随报价出具的规格书与批次COA为准。
| CAS 号 | 1119-34-2 |
|---|---|
| 分子式 | C6H15ClN4O2 (written as C6H14N4O2·HCl) |
| 分子量 | 210.66 |
| EINECS | 214-275-1 (PubChem also lists 239-674-8) |
| 别名 | L-Arginine monohydrochloride, L-Arginine HCl, Arginine hydrochloride |
| 外观 | White crystalline powder |
| 溶解性 | Freely soluble in water; practically insoluble in ethanol and ether |
| 药典收载情况 | FCC · JP (as L-Arginine Hydrochloride) |
规格参数
下表为典型参数——以随报价发送的规格书与批次COA为准。
| 项目 | 规格 | 检测方法 |
|---|---|---|
| Arginine content (free base equivalent) | 82.7% theoretical (offer sheet states 83%) | Calculated from molecular weights |
| Assay (as-is / dried basis) | — | Titration or HPLC per the applicable monograph |
| Appearance | — | Visual |
| Identification | — | IR / specific optical rotation per monograph |
| Specific optical rotation | — | Polarimetry |
| Loss on drying | — | Gravimetric |
| Residue on ignition / sulphated ash | — | Gravimetric |
| Chloride | — | Per monograph |
| Sulphate | — | Per monograph |
| Iron | — | Per monograph |
| Other amino acids / related substances | — | TLC or HPLC per monograph |
| Heavy metals (Pb / As / Cd / Hg) | — | ICP-MS or per monograph |
| Microbiology (TAMC / TYMC / E. coli / Salmonella) | — | USP <61>/<62> or equivalent |
表中显示「—」的项目,表示我们没有可对外公布的固定限度:该项目在批次COA中如实报出,限度与您的质检共同确认。宁可留空,也不编一个数字。 完整的理化、重金属与微生物指标见规格书——随每份报价提供。
配方与处理要点
我们技术团队对采购本品的客户必讲的几件事——决定一批货在您工艺里能不能用起来的关键点。
The whole reason to buy the hydrochloride instead of the base is pH. Arginine free base gives a strongly alkaline solution (its guanidino group has a pK around 13); the hydrochloride is the near-neutral form that will not fight an existing beverage buffer. If your formula is a flavoured drink, the HCl salt is almost always the right choice.
The second reason is CO2. The free base absorbs carbon dioxide from air, which slowly forms carbonate and drifts pH and titratable assay; the hydrochloride does not behave that way, which makes it far more forgiving in a plant with open handling.
The cost of both benefits is potency: 82.7% arginine (174.20/210.66) against 100% for the base. A 3000 mg arginine claim needs 3628 mg of the hydrochloride. This is the single most common label error when a formula is switched between arginine forms.
The chloride is not free of consequences. It shows up in the chloride limit test of an amino-acid monograph, in your product's total sodium-chloride-equivalent calculation if you report one, and in corrosion of stainless equipment held wet with concentrated solution.
For parenteral and clinical use, arginine hydrochloride rather than the base is the form with a JP Injection monograph — a useful signal of which form the pharmaceutical world has standardised on.
应用领域
仅面向B2B生产用途——不作任何成品或功效宣称。
各市场法规状态
以资料允许的最保守口径陈述原料的法规状态。这是供应链信息,不构成法规意见——成品与目的地市场的合规判断请咨询您自己的法规顾问。
| 市场 | 状态 | 依据 |
|---|---|---|
| United States | Listed by name in FDA's food-additive regulation for amino acids as 'L-Arginine'. That regulation permits use as a nutrient 'to significantly improve the biological quality of the total protein' of a food, subject to a cap of 6.6 percent by weight of the total protein of the finished food, and to the labelling requirements in paragraph (e). It is not a general-purpose clearance for any food use, and it is not the authority under which dietary supplements are marketed — those sit under DSHEA and 21 CFR part 111. | 21 CFR 172.320(a), (b), (c)(4), (e) |
| European Union | Amino acids are not covered by the harmonised positive lists of Directive 2002/46/EC (Annexes I and II of that Directive cover vitamins and minerals only). Amino acid ingredients are therefore governed by general EU food law plus national rules, with mutual recognition under Article 4 of Regulation (EC) No 764/2008 in practice. | Directive 2002/46/EC (food supplements); national member-state rules |
| Japan | An Official Monograph titled 'L-Arginine Hydrochloride' is listed in the Japanese Pharmacopoeia, Eighteenth Edition. Monograph existence only — no limits transcribed. | JP XVIII, Official Monographs |
| China | Status as a nutrient fortification substance / food additive under Chinese national standards to be confirmed. | GB 14880-2012 (nutrient fortification substances), GB 2760 (food additives), and NHC new-food-ingredient announcements |
相关研究文献
本化合物的同行评议文献,标识号均可点击直达原文——不必只听我们说。
以下文献仅用于提供科学背景。它们描述的是针对该化合物已发表的研究,既不是对本原料的宣称,也不是对任何成品的宣称。致诚生物不作任何医疗、健康或功效宣称。
- In a randomised placebo-controlled study in seventeen healthy men, a single 6 g oral dose of L-arginine hydrochloride produced no significant change in plasma nitrite plus nitrate over 120 minutes. Alvares TS, Conte-Junior CA, Silva JT, Paschoalin VM. Nutr Metab (Lond). 2012;9(1):54. PMID 22691607DOI 10.1186/1743-7075-9-54原文
- In a crossover pharmacokinetic study in ten healthy volunteers, the absolute bioavailability of a single 10 g oral dose of L-arginine was approximately 20%. Tangphao O, Grossmann M, Chalon S, Hoffman BB, Blaschke TF. Br J Clin Pharmacol. 1999;47(3):261-266. PMID 10215749DOI 10.1046/j.1365-2125.1999.00883.x原文
- In rats and rabbits, oral supplementation with a combination of L-citrulline and L-arginine produced a more rapid increase in plasma L-arginine and greater enhancement of nitric oxide bioavailability than either compound alone at the same total dose. Morita M, Hayashi T, Ochiai M, Maeda M, Yamaguchi T, Ina K, Kuzuya M. Biochem Biophys Res Commun. 2014;454(1):53-57. PMID 25445598DOI 10.1016/j.bbrc.2014.10.029原文
包装、储存与交期
| 标准包装 | 25kg袋装、箱装或桶装 |
|---|---|
| 定制包装 | 长期客户可安排定制包装与标签 |
| 储存条件 | 阴凉干燥处,原包装密封保存 |
| 交期 | undefined |
| 运输 | 上海海运/空运拼货 · FOB/CIF/DDP按航线 |
